Dextrose skrev:
Jeg har aldrig helt forstået hvad risici er ved at indtage Tyramin - jeg har lædt om hovedpine, men aldrig om dødsfald?
http://www.maps.org/news-letters/v06n1/06158mao.html skrev:
Tyramine stimulates the release of norepinephrine in the bloodstream and its absorption is blocked by MAOI. Sufficient exposure can therefore cause a norepinephrine surge resulting in hypertension. Symptoms include nausea, occipital headache, and even intracranial hemorrhage.
Increased norepinephrine release is also compounded by stimulants, including amphetamines and other amines. Due to the amphetamine properties of the phenethylamine entheogens, mescaline and MDMA ("Ecstasy"), a hypertensive crisis could ensue as a result of their combination with an MAOI. Such an interaction has been reported in the literature.(5)
Contraindications to the use of MAOIs include severe liver and kidney impairment, severe or frequent headache, uncontrolled hypertension, cardiovascular diseases, and cerebrovascular diseases.
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