Dex> Jeg tror bestemt at den kombination kunne være en fantastisk psykedelisk oplevelse, men 5-MeO-DMT er jo som bekendt NOGET stærkere end N,N-DMT. Kemisk ren N,N-DMT ville jeg ikke have SÅ store skrupler ved at tage som "pharmahuasca".
Til de fleste ayahuasca-brygge skal der indtages ret store og letafmålelige mængder plantemateriale, hvad enten planterne indeholder mest DMT eller 5-MeO-DMT. For derimod at ramme dosen af kemisk ren 5-MeO-DMT rigtigt, er det nødvendigt at have afvejet mængden på en ret nøjagtig og pålidelig vægt. I modsætning til N,N-DMT, har jeg læst flere rapporter der tyder på at det slet ikke er umuligt at indtage så meget 5-MeO-DMT at det bliver akut helbredstruende. Ved rygning af substansen giver det ret meget sig selv hvornår man har fået nok
, men hvis man har saboteret sit MAO-system effektivt med f.eks. harmalin og indtaget en dosis oralt, vil der nok gå 15 - 20 minutter før man har nogen anelse om hvilken intensitet trippet bliver - og da vil det sikkert ikke hjælpe meget at forsøge at kaste op hvis man føler at man har fået for meget.
Erowid anbefaler heller ikke ligefrem kombinationen:
Citat:
5-MeO-DMT and MAOIs :
Although 5-MeO-DMT is present in some plants used in ayahuasca and in some ayahuasca brews, Erowid has received several reports of very troubling physical reactions in people who have ingested 5-MeO-DMT with MAOI harmala-alkaloids. There appears to be the risk of severe hypertensive symptoms, overheating, serotonin syndrome, etc. However its important to note that this contraindication is still speculative, because of the long history of use of brews containing the two in combination.
A case of a 17-year-old male was reported to us in December 2002. He ingested an extract of Syrian Rue and then smoked an unknown (but large) dose of powdered, chemical 5-MeO-DMT. He quickly became non-responsive and fell to the ground, began convulsing (myoclonic jerking), and his sitter called an ambulance for help. He was found to have had a pulse of 180, blood pressure 200/125, and temperature 106.0 F. These levels are dangerously high. He was minimally responsive but became wildly agitated upon stimulation (even just speaking to him). He was treated with diazepam and transferred by helicopter to a Boston area hospital. The patient may have suffered lasting damage to his kidneys and rhabdomyolysis. A formal case report of this incident is expected to appear in a medical journal in the next 12 months.
We have also received some reports from groups experimenting with making pharmahuasca using 5-MeO-DMT who have said that they had much higher incidence of bad reactions with 5-MeO-DMT than with N,N-DMT. They discontinued using the 5-MeO-DMT.
...Så nej tak, den tror jeg pænt jeg springer over...
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