A/B-ekstrakter af plantemateriale sviner som regelt af helvede til, og kræver ofte store mængder startmateriale.
Jeg foreslår følgende i stedet som nemt kan opskaleres, hvis i ønsker at bryde loven. Tryptamin kan substitueres med 5-MeO-Tryptamin, hvis man ønsker korresponderende dialkylering.
Men jeg vil ikke anbefale at i gør det, da det er meget kriminelt!
Citat:
DMT by reductive methylation of Tryptamine with 37% Formaldehyde and NaBH3CN in Methanol1
Tryptamine (1.12g, 7 mmol), Sodium Cyanoborohydride (0.88g, 14 mmol) and Glacial Acetic Acid (2ml, 35 mmol) was dissolved in 110ml Methanol at 0°C, and a solution of 37% Formaldehyde (1.4 mL, 18.5 mmol) in 15ml Methanol was added dropwise over 20 min, and the resulting solution was allowed to stir for 20 min at 0°C and 2.5h at room temp. The methanol was evaporated under reduced pressure, and 80ml 25% aqueous potassium carbonate was added and the solution extracted with 2x125ml EtOAc, the extracts washed with 2x40ml brine, dried over MgSO4and the solvent evaporated under reduced pressure to give an amber oil, which was purified by flash chromatography on 30g silica gel (using a gradient of EtOAc:MeOH) to give an oil, which was crystallized from boiling hexane to give N,N-Dimethyltryptamine as colorless waxy crystals, weighing 0.9g (69%).
Synthesis of DMT (and analogs) from Tryptamine
