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My friend's looking into 5-HTP recently, he's very fascinated by it. He can't seem to find any information about the above question though.

As far as he is aware, 5-HTP produces serotonin but does not necessarily release it (like MDMA does). His question is, if enough 5-HTP was consumed to produce enough serotonin, would the body try to release it? And if so, would that release give him a buzz/high?

Secondly, if he consumes 5-HTP to produce serotonin, and then consumes MDMA, would he experience a better/stronger/higher trip?

Svar:

The mechanism of serotonin production is under repressible control- meaning it prevents excess amounts of accumulated serotonin by slowing down production, aka feedback inhibition. That being said, swim has felt a pleasurable "high" a handful of times but it is hit or miss. It usually just consists of a drowsy type of feeling. For the question about mdma UTFSE.
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Hydroxy, check out this Erowid report: http://www.erowid.org/experiences/exp.php?ID=42885

It certainly seems to indicate the possibility of the combination being amazing, however I do wonder about the safety of such a high amount of 5-htp and whether serotonin syndrome would be a risk. Can anyone comment on the safety of what the person in this erowid report did?

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friend of mine and another user of this forum hempy666 has a friend who has injected 5-htp cant remember what his friends results were.(pm him with a link to this thread if you want to know)
grandma loves 5-htp she finds it increases the effects of pot and dxm greatly even thought many claim mixing it with dxm is risky,she has yet to find/see any evidence confirming that anyone has had problems mixing these two.

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My friend says thanks for the responses - he found an old thread after sifting through this forum. He notices much talk of piracetam and 5-HTP. Some people say 5-HTP hasn't enhanced the roll at all, in fact in some cases it weakens it. Others say it makes their roll better. Strange how it varys. My friend guesses there's only one way to find out how it affects him... He is just unsure how much to take.
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Swim finds 5-HTP will give him a mild mood lift in the form of patience but once that wears off, swim will feel sleepy (which is almost never when hes stright)


Swim always preloads and doesn't notice an different on the roll, the preload is all about the day after. Swim finds preloading 100mg of 5-HTP each night, 5 nights before the roll and 100mg the morning of his roll then 300mg the morning after his roll bring his head round quicker and has yet to suffer the crippling blues he once had without 5-HTP.


L-tyrosine give a caffeine type buzz and gives the initial come up a speedy buzzy feel that fades into the roll nicely though.

If swiy's not planning to preload that week, take around 400mg. Some say it can make you feel sick but swim never does - this has not affected swims roll he doesn't think.
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My friend is doing a little experiment. He is going to consume MDMA on 5-Jan-08. On 17-Dec-07 he got some 5-HTP and has been taking 3 x 100mg daily. He will continue this dosage until 5-Jan-08 and see what happens.

What he has discovered so far, even after just six days of dosing, his mood has generally been a lot happier and he is sleeping so much better. Is this normal or is this just placebo?

He will post his findings here after the 5-Jan-08 event.

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Totally normal. Cant recomend 5-HTP enough.