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Health effects
Use of inhalants can cause brain, nerve, liver and other damage to the body. Some inhalants can also indirectly cause sudden death by cardiac arrest, in a syndrome known as Sudden Sniffing Death Syndrome. The anesthetic gases present in the inhalants appear to sensitize the user to adrenaline. In this state a sudden surge of adrenaline (e.g., from a frightening hallucination), can cause a fatal cardiac arrhythmia. [7]
In the short term, death from solvent abuse occurs most commonly from aspiration of vomit while unconscious, or from a combination of respiratory depression and hypoxia, the second cause being especially a risk with heavier than air vapors such as butane or gasoline vapor. Deaths typically occur from complications related to excessive sedation and vomiting. Actual overdose from the drug does occur, however, and indeed inhaled solvent abuse is statistically more likely to result in life-threatening respiratory depression than intravenous use of opiates such as heroin.
Most deaths from solvent abuse could be prevented if individuals were rescusitated quickly when they stopped breathing and their airway cleared if they vomited. However, most inhalant abuse takes place when people inhale solvents by themselves or in groups of people who are intoxicated. Certain solvents are more hazardous than others, such as gasoline or refrigerant gases.
Hypoxia can occur when inhalant users are huffing from a plastic bag over their face, which means that they are not breathing enough fresh air. However, some inhalants are heavier-than-air gases or vapors, and, if regular breathing is not maintained, they will remain in the lungs instead of being naturally expelled. Also, since many solvents are highly flammable (e.g., gasoline, paint thinner), some users have suffered burn injuries and deaths due to fires.
Woman inhalant users who become pregnant may have adverse effects on the fetus. The baby may be smaller, and may need additional health care. There is some evidence of birth defects and disabilities in babies born to women who sniffed solvents such as gasoline.
Driving while using solvents presents the same dangers as other types of impaired driving. One well-publicized event in early 1999 in the United States illustrated the potential dangers of inhalant abuse, when five high school girls were killed in a car accident outside Philadelphia. The coroner's report showed that four of the five, including the driver, had ingested "significant" amounts of a computer keyboard cleaner.
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