Psychedelia.dk

virkningsstoffet der er i Motiron; methylphenidat er beslægtet med Amfetamins molekyle opbygning..
De giver dig et kick, og vil sådan set virke som Amfetamin.. Men mange tager fejl og tror der er Amfetamin i selve Motiron pillerne men det er altså forkert..

It is most commonly formed when ethanol and methylphenidate are coingested, via hepatic transesterification.[1] Ethylphenidate formation appears to be more common when large quantities of methylphenidate and alcohol are consumed at the same time, such as in non-medical use or overdose scenarios.[2] This carboxylesterase-dependent transesterification process is also known to occur when cocaine and alcohol are consumed together, forming cocaethylene.[3]

Ethylphenidate is more selective to the dopamine transporter (DAT) than methylphenidate, having approximately the same efficacy as the parent compound,[4] but has significantly less activity on the norepinephrine transporter (NET).[5] It has nearly an identical dopaminergic pharmacodynamic profile as methylphenidate, possessing appreciable affinity for the inhibitory G protein-coupled dopamine subtype-2 receptors in the striatum and mesolimbic regions of the brain,[6] including the nucleus accumbens,[7] which is primarily responsible for its euphoric and reinforcing effects.[8]

Interestingly, the eudysmic ratio for ethylphenidate is superior to that seen for TMP.[4]"

Cocaethylene appears to, in most users, produce more euphoria and possess a longer duration of action than cocaine. Some studies suggest that it may have a higher cardiovascular toxicity than cocaine. Cocaethylene is more potent than cocaine at binding to the dopamine transporter, however it is less potent at binding to the serotonin transporter and norepinephrine transporter.[3][4]

hvis det minder om kokain, vil jeg da lige høre hvor vanedannende de er

Jeg fandt lige noget jeg synes var interessant angående methylphenidate og alcohol indtag:



http://en.wikipedia.org/wiki/Ethylphenidate

Hvor meget er en række? Et ark med 10 stk?

Jah 10 piller, 5 piller x 2 rækker på hvert ark eller plade eller hva det end hedder..
Sådan er det i hvert fald med de fleste medicin pakker herhjemme i DK..

Har i hvert fald ikke set andre "størrelser" på ark og har da fået meget forskelligt medicin med tiden..

Kan være han ikke har haft brug for viagra som du har
Eller for den sags skyld stiftet bekendtskab med det.

Så det vil sige at det blir mere euforisk med alkohol?

Så blev jo helt klart hooked, hvilket i mange tilfælde er tegn på hvor vanedannende det er.. (o.O)
eller misforstår jeg ordet vanedannende??

According to this publication if I have read it correctly approximately 2.3% is converted with moderate alcohol consumption and methylphenidate, maybe a good starting point in reference to dosing.

http://dmd.aspetjournals.org/content/28/6/620.full "