Uf, den er lidt svær Cocaman, for der er nogle mærkelige mekanismer der spiller ind der mener jeg. Googlede og fandt det her ang. "precipitaed withdrawals"
"This is where the danger of precipitated withdrawal arises. With buprenorphine’s strong receptor-binding affinity, when given to a person who is already addicted to heroin, the buprenorphine removes and then replaces the heroin molecules that have already attached to the person’s opioid receptors in the brain. As a result of this, the buprenorphine produces a significantly reduced opioid reaction (as it should). But the effect of millions of receptors being deprived of their full opioid agonist and instead being replaced by a partial opioid agonist (that, by design, has a weakened effect) can trigger withdrawal symptoms in the person." -
https://americanaddictioncenters.org/su ... withdrawalSå du skal passe på du ikke fremprovokere abstinenser med den kombo der.